Feedback

Natural products in treating diabetic kidney disease: a visualized bibliometric analysis

Affiliation
Department of Pharmacy ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Liu, Tianlong;
Affiliation
Department of Pharmacy ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Li, Xiaolin;
Affiliation
Department of Pharmacy ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Chen, Yidan;
Affiliation
Department of Pharmacy ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Li, Jinhu;
Affiliation
Department of Pharmacy ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Wang, Rong;
Affiliation
Department of Pharmacy ,Xijing Hospital ,Fourth Military Medical University ,Xi’an ,China
Ding, Yi;
Affiliation
Fundamental Medical Science Research Laboratories and Department of Nephrology ,The 940th Hospital Joint Logistics Support Forces of PLA ,Lanzhou ,China
Liu, Minna

Background Diabetic kidney disease (DKD) is one of the most significant complications in diabetic patients, yet current therapeutic options are limited. The advantages of natural products in treating chronic diseases have increasingly garnered attention. This study aims to map the landscape of natural products in DKD and provide new insights for future research in this field. Methods Literature retrieval was conducted through the Web of Science. CiteSpace and VOSviewer were employed to conduct visual analyses of these papers. Results A total of 523 literature were obtained, originating from 655 institutions across 40 countries/regions and involving 3,116 authors. These literature were published in 178 journals. The results indicate that China leads in this field, with Li Ping contributing the most publications. Zhang Lei’s work has been cited the most. Journal of Ethnopharmacology is the most popular journal. The paper with the highest average annual citation rate is authored by Tang, GY. Keyword analysis reveals that systematic biological approaches such as network pharmacology, molecular docking, and gut microbiota have become hotspots in this field. Conclusion Natural products exhibit positive pharmacological activity and therapeutic value in the treatment of DKD. Extensive cooperation and communication among countries, institutions, and authors still need to be strengthened to promote basic research and clinical applications of natural products. Besides, the deep integration of network pharmacology with artificial intelligence and big data represents a hot topic and trend in future research on natural products against DKD.

Graphical Abstract

Cite

Citation style:
Could not load citation form.

Access Statistic

Total:
Downloads:
Abtractviews:
Last 12 Month:
Downloads:
Abtractviews:

Rights

License Holder: Copyright © 2025 Liu, Li, Chen, Li, Wang, Ding and Liu.

Use and reproduction: