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Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology

Affiliation
College of Physics and Optoelectronic Engineering ,Shenzhen University ,Shenzhen ,China
Li, Chao;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Du, Ming;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Han, Yujie;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Sun, Wentao;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Chen, Zixi;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Liu, Qiong;
Affiliation
School of Life Sciences and Food Engineering, Hanshan Normal University ,Chaozhou ,Guangdong ,China
Zhu, Hui;
Affiliation
College of Chemistry and Environmental Engineering ,Shenzhen University ,Shenzhen ,China
Zhao, Liqing;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Li, Shuangfei;
Affiliation
Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science ,Shenzhen Engineering Laboratory for Marine Algal Biotechnology ,Guangdong Provincial Key Laboratory for Plant Epigenetics ,College of Life Sciences and Oceanography ,Shenzhen University ,Shenzhen ,China
Wang, Jiangxin

Microalgae are emerging as a key player in healthcare, functional foods, and sustainable biotech due to their capacity to produce bioactive compounds like β-glucans, omega-3 fatty acids, and antioxidants in an eco-friendly manner. This review comprehensively discusses the role of microalgae in healthcare and functional foods, focusing particularly on β-glucan therapeutics, drug delivery innovations, and synthetic biology applications. In healthcare, microalgae-derived compounds show immense promise for treating diseases, boosting immunity, and tackling oxidative stress. Euglena -derived paramylon, a type of β-glucan, has shown potential in various medical applications, including immunomodulation and anticancer therapy. Synthetic biology and bioprocess engineering are enhancing microalgae’s therapeutic and nutritional value, with applications in drug delivery and personalized medicine. To maximize the potential of microalgae, further research and development are needed to address scalability, regulatory alignment, and consumer acceptance, with a focus on interdisciplinary collaboration and sustainable practices to align healthcare innovation with environmental conservation.

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License Holder: Copyright © 2025 Li, Du, Han, Sun, Chen, Liu, Zhu, Zhao, Li and Wang.

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