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The role and application of bioinformatics techniques and tools in drug discovery

Affiliation
Department of Infectious Diseases ,The First Affiliated Hospital ,College of Clinical Medicine ,Henan University of Science and Technology ,Luoyang ,Henan ,China
Zhang, Shujun;
Affiliation
Department of Infectious Diseases ,The First Affiliated Hospital ,College of Clinical Medicine ,Henan University of Science and Technology ,Luoyang ,Henan ,China
Liu, Kaijie;
Affiliation
Department of Infectious Diseases ,The First Affiliated Hospital ,College of Clinical Medicine ,Henan University of Science and Technology ,Luoyang ,Henan ,China
Liu, Yafeng;
Affiliation
Department of Infectious Diseases ,The First Affiliated Hospital ,College of Clinical Medicine ,Henan University of Science and Technology ,Luoyang ,Henan ,China
Hu, Xinjun;
Affiliation
Department of Oncology ,The First Affiliated Hospital ,College of Clinical Medicine ,Henan University of Science and Technology ,Luoyang ,Henan ,China
Gu, Xinyu

The process of drug discovery and development is both lengthy and intricate, demanding a substantial investment of time and financial resources. Bioinformatics techniques and tools can not only accelerate the identification of drug targets and the screening and refinement of drug candidates, but also facilitate the characterization of side effects and the prediction of drug resistance. High-throughput data from genomics, transcriptomics, proteomics, and metabolomics make significant contributions to mechanics-based drug discovery and drug reuse. This paper summarizes bioinformatics technologies and tools in drug research and development and their roles and applications in drug research and development, aiming to provide references for the development of new drugs and the realization of precision medicine.

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License Holder: Copyright © 2025 Zhang, Liu, Liu, Hu and Gu.

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