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Dihydromyricetin: an emerging compound with comprehensive effects on multiple systems

Affiliation
College of Integrative Medicine ,Fujian University of Traditional Chinese Medicine ,Fuzhou ,China
He, Chengyi;
Affiliation
Department of Vascular Surgery ,Union Hospital ,Tongji Medical College ,Huazhong University of Science and Technology ,Wuhan ,China
Chen, Yunfei;
Affiliation
Health Management Center ,Union Hospital ,Tongji Medical College ,Huazhong University of Science and Technology ,Wuhan ,China
Xie, Jiao;
Affiliation
Department of Infectious Diseases ,Union Hospital ,Tongji Medical College ,Huazhong University of Science and Technology ,Wuhan ,China
Luo, Miao;
Affiliation
Department of Medical Biosciences ,Faculty of Natural Sciences ,University of The Western Cape ,Cape Town ,South Africa
Fisher, David;
Affiliation
Hai Phong University of Medicine and Pharmacy ,Haiphong ,Vietnam
Hien, Nguyen Thi Thu;
Affiliation
The Research Institute of Virology ,Ministry of Health ,Tashkent ,Uzbekistan
Musabaev, Erkin;
Affiliation
Department of Vascular Surgery ,Union Hospital ,Tongji Medical College ,Huazhong University of Science and Technology ,Wuhan ,China
Dang, Yiping;
Affiliation
Department of Infectious Diseases ,Union Hospital ,Tongji Medical College ,Huazhong University of Science and Technology ,Wuhan ,China
Zhao, Lei;
Affiliation
Department of Vascular Surgery ,The Affiliated People’s Hospital of Fujian University of Traditional Chinese Medicine ,Fuzhou ,China
Xia, Yin

Dihydromyricetin (DHM or DMY) is a flavonoid derived from natural sources with a range of confirmed biological benefits. It exhibits anti-inflammatory, antioxidant, anti-tumor, and anti-viral activities. DHM is recognized for its high biosafety, making it a promising subject for further research. This article offers a comprehensive overview of DHM’s pharmacological properties, mechanisms, and recent research developments in the cardiovascular, urinary, digestive, nervous, and respiratory systems. The review summarizes DHM’s biological effects and associated signaling pathways, providing novel insights for its clinical application.

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Published in:
Frontiers in Pharmacology  
Vol. 15 (03.01.2025)
Volume:
15
Date Issued:
03.01.2025
DOI:
10.3389/fphar.2024.1488003
Language:
English
Type of Resource:
Text
Keywords:
dihydromyricetin; anti-inflammatory; antioxidant; anti-virus; signaling pathway
DDC:
610 Medizin und Gesundheit

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License Holder: Copyright © 2025 He, Chen, Xie, Luo, Fisher, Hien, Musabaev, Dang, Zhao and Xia.

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