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Promising treatment biomarkers in asthma

Affiliation
Department of Medicine ,Section of Respiratory Medicine ,Herlev-Gentofte Hospital ,Hellerup ,Denmark
Bonnesen, Barbara;
Affiliation
Department of Medicine ,Section of Respiratory Medicine ,Herlev-Gentofte Hospital ,Hellerup ,Denmark
Jensen, Jens-Ulrik S.;
Affiliation
Division of Immunology ,Immunity to Infection and Respiratory Medicine ,School of Biological Sciences ,The University of Manchester ,Manchester ,United Kingdom
Mathioudakis, Alexander G.;
Affiliation
Department of Respiratory Medicine ,Nicolae TestemiĊ£anu State University of Medicine and Pharmacy ,Chisinau ,Moldova
Corlateanu, Alexandru;
Affiliation
Department of Medicine ,Section of Respiratory Medicine ,Herlev-Gentofte Hospital ,Hellerup ,Denmark
Sivapalan, Pradeesh

Asthma is a highly heterogenous disease which researchers over time have attempted to classify into different phenotypes and endotypes to improve diagnosis, prognosis and treatment. Earlier classifications based on reaction to environmental allergens, age, sex and lung function have evolved, and today, the use of precision medicine guided by biomarkers offers new perspectives on asthma management. Identifying biomarkers that may reveal the underlying pathophysiology of the disease will help to select the patients who will benefit most from specific treatments. This review explores the classification of asthma phenotypes and focuses on the most recent advances in using biomarkers to guide treatment.

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License Holder: Copyright © 2023 Bonnesen, Jensen, Mathioudakis, Corlateanu and Sivapalan.

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