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Therapeutic approaches for chronic hepatitis C: a concise review

Affiliation
Joslin Diabetes Center ,Harvard Medical School , Harvard University,Boston ,MA ,United States
Nawaz, Allah;
Affiliation
Department of Surgery ,Bahawal Victoria Hospital ,Bahawalpur ,Pakistan
Manzoor, Azhar;
Affiliation
Department of Medicine, and Surgery ,Rawalpindi Medical University ,Rawalpindi ,Punjab ,Pakistan
Ahmed, Saeed;
Affiliation
Department of Pharmacy ,University of Poonch Rawalakot ,Rawalakot ,Azad Jammu and Kashmir (AJ&K) ,Pakistan
Ahmed, Naveed;
Affiliation
Department of Molecular and Medical Pharmacology ,Faculty of Medicine ,University of Toyama ,Toyama ,Japan
Abbas, Waseem;
Affiliation
Department of Clinical Laboratory Sciences ,College of Applied Medical Sciences ,King Khalid University ,Abha ,Saudi Arabia
Mir, Mushtaq Ahmad;
Affiliation
First Department of Internal Medicine ,Faculty of Medicine ,University of Toyama ,Toyama ,Japan
Bilal, Muhammad;
Affiliation
Jammu Institute of Ayurveda and Research ,University of Jammu ,Jammu ,India
Sheikh, Alisha;
Affiliation
Cardiovascular Center of Excellence ,Louisiana State University Health Sciences Center ,New Orleans ,LA ,United States
Ahmad, Saleem;
Affiliation
Department of Molecular and Medical Pharmacology ,Faculty of Medicine ,University of Toyama ,Toyama ,Japan
Jeelani, Ishtiaq;
Affiliation
Department of Molecular and Medical Pharmacology ,Faculty of Medicine ,University of Toyama ,Toyama ,Japan
Nakagawa, Takashi

Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon/ribavirin therapy historically pivotal in HCV management and herbal approaches rooted in traditional and complementary medicine. Advancements in therapeutic development and enhanced clinical outcomes axis on a comprehensive understanding of the diverse HCV genome, its natural variations, pathogenesis, and the impact of dietary, social, environmental, and economic factors. A thorough analysis was conducted through reputable sources such as Science Direct, PubMed, Scopus, Web of Science, books, and dissertations. This review primarily focuses on the intricate nature of HCV genomes and explores the potential of botanical drugs in both preventing and treating HCV infections.

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License Holder: Copyright © 2024 Nawaz, Manzoor, Ahmed, Ahmed, Abbas, Mir, Bilal, Sheikh, Ahmad, Jeelani and Nakagawa.

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