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The applications of functional materials-based nano-formulations in the prevention, diagnosis and treatment of chronic inflammation-related diseases

Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Wang, Jingjing;
Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Ni, Rui;
Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Jiang, Tingting;
Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Peng, Dan;
Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Ming, Yue;
Affiliation
Medical Research Institute ,Southwest University ,Chongqing ,China
Cui, Hongjuan;
Affiliation
Department of pharmacy ,Daping Hospital ,Army Medical University ,Chongqing ,China
Liu, Yao

Chronic inflammation, in general, refers to systemic immune abnormalities most often caused by the environment or lifestyle, which is the basis for various skin diseases, autoimmune diseases, cardiovascular diseases, liver diseases, digestive diseases, cancer, and so on. Therapeutic strategies have focused on immunosuppression and anti-inflammation, but conventional approaches have been poor in enhancing the substantive therapeutic effect of drugs. Nanomaterials continue to attract attention for their high flexibility, durability and simplicity of preparation, as well as high profitability. Nanotechnology is used in various areas of clinical medicine, such as medical diagnosis, monitoring and treatment. However, some related problems cannot be ignored, including various cytotoxic and worsening inflammation caused by the nanomaterials themselves. This paper provides an overview of functional nanomaterial formulations for the prevention, diagnosis and treatment of chronic inflammation-related diseases, with the intention of providing some reference for the enhancement and optimization of existing therapeutic approaches.

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License Holder: Copyright © 2023 Wang, Ni, Jiang, Peng, Ming, Cui and Liu.

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