Feedback

Relevance of Visual Acuity Measurement for Therapeutic Decisions in Diabetic Macular Edema

ORCID
0000-0002-1418-1872
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
Mathis, Thibaud;
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
El Ameen, Batoul;
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
Vartin, Cristina;
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
Serrar, Yasmine;
ORCID
0000-0002-6180-3937
Affiliation
Centre Monticelli Paradis, 13008 Marseille, France;
Matonti, Frédéric;
Affiliation
MS Sudhalkar Medical Research Foundation, Baroda 390001, India;
Sudhalkar, Aditya;
ORCID
0000-0001-8403-0853
Affiliation
Alphavision Augenarztpraxis, 27568 Bremerhaven, Germany;
Bilgic, Alper;
ORCID
0000-0001-6110-2113
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
Rezkallah, Amina;
ORCID
0000-0002-3908-6716
Affiliation
Service d’Ophtalmologie, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France;(T.M.);(B.E.A.);(C.V.);(Y.S.);(A.R.)
Kodjikian, Laurent

This study aimed to determine the validity of basing retreatment decisions on anatomical criteria alone (captured using optical coherence tomography (OCT)—OCT-guided strategy) rather than the gold standard (combined visual acuity (VA) and OCT) in patients with diabetic macular edema (DME). This cross-sectional study included 81 eyes undergoing treatment for DME from September 2021 to December 2021. An initial therapeutic treatment decision based on OCT results was made on inclusion. Subsequently, in light of the patient’s VA score, this initial decision was upheld or adjusted, and the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. In 67 out of the 81 eyes included in the study (82.7%), the OCT-guided strategy produced equivalent results to the gold standard. In this study, the OCT-guided retreatment decision strategy yielded sensitivity and specificity of 92.3% and 73.8%, respectively, and PPV and NPV of 76.6% and 91.2%, respectively. These findings differed according to the patient’s treatment regimen: the sensitivity and specificity for eyes under a treat and extend regimen was higher, 100% and 88.9%, respectively, than eyes under a Pro Re Nata regimen, 90% and 69.7%, respectively. These findings show that VA testing could be omitted from the follow-up of certain patients with DME treated with intravitreal injections without impacting the quality of care.

Cite

Citation style:
Could not load citation form.

Access Statistic

Total:
Downloads:
Abtractviews:
Last 12 Month:
Downloads:
Abtractviews:

Rights

License Holder: © 2023 by the authors.

Use and reproduction: