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Recent Advances in Pharmaceutical Approaches of Antimicrobial Agents for Selective Delivery in Various Administration Routes

Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Marzaman, Ardiyah Nurul Fitri;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Roska, Tri Puspita;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Sartini, Sartini;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Utami, Rifka Nurul;
ORCID
0000-0003-0035-5955
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Sulistiawati, Sulistiawati;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Enggi, Cindy Kristina;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Manggau, Marianti A.;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Rahman, Latifah;
Affiliation
Institute for Macromolecular Chemistry, Albert Ludwigs Universitat Freiburg, 79085 Freiburg, Germany;
Shastri, Venkatram Prasad;
Affiliation
Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia;(A.N.F.M.);(T.P.R.);(S.S.);(R.N.U.);(S.S.);(C.K.E.);(M.A.M.);(L.R.)
Permana, Andi Dian

Globally, the increase of pathogenic bacteria with antibiotic-resistant characteristics has become a critical challenge in medical treatment. The misuse of conventional antibiotics to treat an infectious disease often results in increased resistance and a scarcity of effective antimicrobials to be used in the future against the organisms. Here, we discuss the rise of antimicrobial resistance (AMR) and the need to combat it through the discovery of new synthetic or naturally occurring antibacterial compounds, as well as insights into the application of various drug delivery approaches delivered via various routes compared to conventional delivery systems. AMR-related infectious diseases are also discussed, as is the efficiency of various delivery systems. Future considerations in developing highly effective antimicrobial delivery devices to address antibiotic resistance are also presented here, especially on the smart delivery system of antibiotics.

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Editor:
Albericio, Fernando
Published in:
Antibiotics  
Vol. 12, No. 5 (27.04.2023)
Volume:
12
No.:
5
Date Issued:
27.04.2023
DOI:
10.3390/antibiotics12050822
Language:
English
Type of Resource:
Text
Keywords:
antimicrobial resistance; antimicrobials; pharmaceutical preparations; selective delivery
Subject of DNB:
610 Medical sciences Medicine

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