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Case report: An autopsy case of pilsicainide poisoning

Affiliation
Department of Forensic Medicine Faculty of Medicine ,Kagawa University ,Kagawa ,Japan
Takei, Sella;
Affiliation
Department of Forensic Medicine Faculty of Medicine ,Kagawa University ,Kagawa ,Japan
Kinoshita, Hiroshi;
Affiliation
Department of Forensic Medicine Faculty of Medicine ,Kagawa University ,Kagawa ,Japan
Kumihashi, Mitsuru;
Affiliation
Department of Forensic Medicine Faculty of Medicine ,Kagawa University ,Kagawa ,Japan
Jamal, Mostofa;
Affiliation
Bio Design Inc. ,Tokyo ,Japan
Abe, Hiroko;
Affiliation
Department of Forensic Medicine Faculty of Medicine ,Kagawa University ,Kagawa ,Japan
Kimura, Shoji

We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy findings, results of the toxicological examination, and investigation by the authorities, we concluded that the cause of death was due to pilsicainide poisoning.

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Published in:
Frontiers in Pharmacology
Vol. 14 (26.01.2023)
Volume:
14
Date Issued:
26.01.2023
DOI:
10.3389/fphar.2023.1090265
Language:
English
Type of Resource:
Text
Keywords:
pilsicainide; poisoning; pro-arrhythmia; anti-arrhythmic agent; autopsy
DDC subject of DNB:
610 Medical sciences Medicine

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License Holder: Copyright © 2023 Takei, Kinoshita, Kumihashi, Jamal, Abe and Kimura.

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