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Intraoperative Optical Coherence Tomography in the Management of Macular Holes: State of the Art and Future Perspectives

ORCID
0000-0003-4079-8881
Affiliation
Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway
Confalonieri, Filippo;
ORCID
0000-0002-6549-3171
Affiliation
Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Institute for Clinical Medicine, University of Oslo, Kirkeveien 166, 0450 Oslo, Norway
Haave, Hanna;
Affiliation
Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway
Bragadottir, Ragnheidur;
Affiliation
Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway
Stene-Johansen, Ingar;
Affiliation
Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Institute for Clinical Medicine, University of Oslo, Kirkeveien 166, 0450 Oslo, Norway
Lumi, Xhevat;
Affiliation
Department of Ophthalmology, Justus Liebig University Giessen, University Hospital Giessen and Marburg GmbH, 35392 Giessen, Germany
Lytvynchuk, Lyubomyr;
ORCID
0000-0003-2905-9252
Affiliation
Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway
Petrovski, Goran

Background: Non-invasive diagnostic technologies in ophthalmology have substantially transformed contemporary clinical practice. Intraoperative optical coherence tomography (iOCT) systems have recently been used for various surgical interventions, including the treatment of full-thickness macular holes (FTMHs). Materials and Methods: We conducted a systematic review on the use of iOCT and its possible benefits in the management of FTMHs, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA). The level of evidence according to the Oxford Centre for Evidence-Based Medicine (OCEM) 2011 guidelines, and the quality of evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system, were assessed for all included articles. Results: 1131 articles were initially extracted, out of which 694 articles were obtained after duplicates were removed and their abstracts screened. A total of 65 articles was included for full-text review. Finally, 17 articles remained that fulfilled the inclusion criteria. Conclusions: Even though there is just a small number of studies with solid results, the use of iOCT in FTMH surgery may be a helpful tool for both novice and experienced surgeons planning and managing difficult cases. Additionally, it could be used for teaching reasons and for exploring novel surgical techniques.

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